Youngest Princess of Hoshido and voiced by Brianna Knickerbocker.

Shy and timid by nature, Sakura is very polite to others but is prone to stuttering during her conversations, a fact that becomes especially prominent when she is nervous. She tends to be very easily intimidated when confronted with unfamiliar situations existing outside her comfort zone. These traits of hers particularly stand out when she is compared alongside her older siblings, all of whom are relatively more confident, self-assured and sanguine. Complementing her shy demeanor is a heart of compassion and kindness, a fact that has led to her devoting her life towards the cause of providing healing aid to others in order to alleviate their suffering.

Hidden beneath the folds of Sakura's meekness is a strong will, one that emerges when she is tried by situations that threaten to endanger the lives of her loved ones. This fact is best exemplified through her actions in Chapter 25 on the Birthright route, where she stops Iago from ruining Azura's song to free Takumi from his spells and in Chapter 22 on the Conquest route; although she clearly possesses a disdain for warfare and harbors no desire to attack her sibling, she resolves to personally take up arms against them nevertheless for the sake of defending her homeland from their invasion.

She is the best at healing out of everyone in the army. Her birthday is April 9.