Lisa Lisa is like any Ripple Master, a dignified and courageous woman, facing the Pillar Men without fear, and confidently confronts any challenge she encounters, especially in regards to fighting someone. Lisa Lisa takes some pride in her fighting ability, and tells Joseph that she doesn't need a youngster like him to win. Lisa Lisa is constantly portrayed as a brave woman, being able to bluff Kars into sparing her and Joseph when they are surrounded by vampires without letting any emotion transpire and in the past, immediately killed the zombie who murdered her husband George II, forcing her to hide in Europe.

As the master of Caesar and Joseph, she skilfully employs harsh and apparently life-threatening training for her students, and is severe to Joseph, whose antics she doesn't tolerate during his training. Being the de facto leader of the Ripple Users, she is an authoritative leader and reminds everyone that their emotions are secondary to their goal of defeating the Pillar Men. After Caesar's death, Lisa Lisa tries to maintain an insensitive facade, telling Joseph to immediately focus on the fight. However Joseph points out her loss of composure, upon which she breaks down in tears, illustrating her deep feelings for Caesar as a student and comrade.