Vanderwood is seen to have a disliking towards 707 at the start of the game, often saying he will 'taser' him if he doesn't complete his work on time, which is a very harsh thing to do. Vanderwood seems to be rather shut off from people, including Seven and appears to do everything his 'boss' tells him to do.

His personality seems to change in the after ending, as he changes from the boss's pet to a bit of a risk taker.