As this character is trans I want this character to be voiced by a fellow trans person.  Also!!! She would probably sound like Bimbo the dog in swing you sinners! 

A 1930s cartoon star. A trouble inclined rubberhose mutt with a wonder for the unnatural and strange, a love for the outsider and scary, and an inclination for the supernatural and horrific. Despite being associated with horrors and nightmares from the edges of imagination Maisy the Mutt is is a benevolent friend to all in need of a friend. This is a very particular role.

This character would not have the stereotypical accent afforded to most 30's inspired characters