Omega infected Doc near the end of Season 2, which caused a massive change in personality. This version of O'Malley is present for the longest of the versions present in The Blood Gulch Chronicles and is characterized as an over-the-top, monologue spewing megalomaniac, serving as a parody of typical super villains. This O'Malley has expressed a wish to annihilate both teams, either to destroy or take over the universe and to "crush every living soul into dust." He expresses these desires in long monologues (with a tendency to overuse the words "fool" and "folly") accompanied by extended fits of evil laughter and extreme close-up shots of his visor.